Differences in Clinical Characteristics, Results and Management of Patients Referred for Pharmacologic Cardiac Stress SPECT Depending on the Protocol Used

Topic: 2. Ischemic Heart Disease


Introduction and Objectives

Pharmacologic cardiac stress SPECT (PS-SPECT) is recommended for non-invasive evaluation of ischemic heart disease (IHD) in patients unable to exercise. Drugs used for stress in our centre are Dipyridamole (DIP) and Dobutamine (DBT). DIP can be associated to exercise (ex-DIP). The objective of the study is to evaluate the diagnostic capacity of the different strategies.

Materials and Methods

Role of Testosterone in the Treatment of Cardiovascular Disease

Cardiovascular disease (CVD) is the most prevalent non-communicable cause of death worldwide.1 The health and economic implications of caring for a growing ageing population with CVD is enormous. Maintaining a “healthy” elderly population that is mobile and independent with a good quality of life is vital. Testosterone is a sex hormone that is predominant in males, being secreted from the testes and adrenal glands, but it also occurs in lower concentrations in females, where it produced in the ovaries.

Practical Applications for Single Pill Combinations in the Cardiovascular Continuum

Cardiovascular disease (CVD) is the leading cause of death worldwide and it is predicted that its incidence will increase markedly, particularly in developed countries, despite the introduction of new drugs and devices. One of the factors accounting for the limited effectiveness of pharmacological therapy is poor adherence to treatment, particularly in elderly patients. The use of combinations of multiple agents in a single pill formulation could be of value in improving adherence to treatment and disease control, as well as conferring other favourable actions.