Peripartum Cardiomyopathy

Ischemic Complications of Pregnancy: Who is at Risk?

Pregnancy is a physiologic challenge, with significant hormonal, metabolic, and hemodynamic changes. Cardiac output is objectively increased by the fifth week after the last menstrual period and continues to grow by approximately 45 % by 24 weeks in the normal, singleton pregnancy. This is facilitated by elevations in heart rate and stroke volume and a decrease in systemic vascular resistance.

Decompensated Heart Failure in Pregnancy

‘Heart failure’ is a term that may be loosely or precisely defined. The development of pulmonary oedema does not necessarily indicate a cardiac cause and of the cardiac causes for pulmonary oedema, not all can be attributed to left ventricular failure.1 The majority of women developing symptoms and signs of heart failure during pregnancy have no known pre-existing cardiomyopathy. This article describes the cardiac causes of pulmonary oedema presenting in pregnancy with reference to other differential diagnoses.

Study links obesity and mood disorders with increased peripartum cardiomyopathy risk

By David Ramsey, Heart Failure 2015, Seville, Spain

Anxiety, depression, bipolar disorder and obesity all place pregnant women at risk of peripartum cardiomyopathy (PPCM), according to a study including nearly 7.5 million pregnant women, presented at Heart Failur 2015. The mood disorders doubled the risk whilst obesity led to a 1.7-fold increase.