Takotsubo Cardiomyopathy

Left Ventricular Dysfunction in the Setting of Takotsubo Cardiomyopathy: A Review of Clinical Patterns and Practical Implications

In the past decades, takotsubo cardiomyopathy (TTC) has emerged as a specific form of acute and transient myocardial disease, predominantly affecting postmenopausal women in the clinical setting.1–4 In general, myocardial involvement in this setting appears to harbour a regional pattern particularly extending beyond the territory of a single coronary artery (and usually without concomitant significant coronary artery disease [CAD]).2,4,5 Mechanistically, sympathetic hyperstimulatio

Cardiac Magnetic Resonance in Takotsubo Syndrome

Takotsubo syndrome (TTS) is an acute, profound, but reversible heart failure syndrome, usually but not always triggered by physical or emotional stress. To date, the exact pathogenic mechanism of this syndrome remains unclear; however, several hypotheses involving vascular mechanisms (i.e. abnormal coronary epicardial or microvascular vasoreactivity),1-3 endocrine and gender-related mechanisms (i.e.

Cardiovascular Disease in Women: Understanding Symptoms and Risk Factors

Globally, cardiovascular disease (CVD) remains the leading cause of mortality in women. Approximately 2.8 million women have been diagnosed with CVD in the UK.1 For many years, the presence of gender-related differences in presentation, risk factors and outcomes have been recognised. Importantly, these discrepancies in presentation and outcomes between the sexes are often associated with inequalities in the detection, referral and management of CVD.

The Role of Cardiovascular Magnetic Resonance Imaging in Heart Failure

Heart failure (HF) can be defined haemodynamically as any abnormality of cardiac structure or function resulting in a failure to deliver oxygen at a rate adequate for tissue requirements, despite normal filling pressures – or only at the expense of increased filling pressures.1 Around half of patients with HF have reduced left ventricle ejection fraction (LVEF; EF <40 %) at rest (HF-REF).2