Atrial Arrhthymias

Drivers of Atrial Fibrillation: Theoretical Considerations and Practical Concerns

The discovery of focal ectopy in the pulmonary veins (PVs) initiating AF1 has resulted in electrical isolation of the PVs forming the mainstay of current treatment strategies. Success rates from PV isolation (PVI) for patients with paroxysmal AF (PAF) are approximately 70–75 %. However, PVI is significantly less effective for those with persistent AF, in whom many studies quote single-procedure success rates of about 50 %.

Atrial Arrhythmias in Pulmonary Hypertension: Pathogenesis, Prognosis and Management

Pulmonary hypertension (PH) is a chronic condition that is characterised by elevated pulmonary vascular pressures and can be caused by several disease processes (see Table 1).1 Regardless of the aetiology, PH is a progressive disease with a clinical course characterised by frequent decompensations in advanced stages and often a poor prognosis despite the development of novel therapeutic agents.2 AF and atrial flutter are common in PH popul

QT Prolongation and Malignant Arrhythmia: How Serious a Problem?

Ventricular repolarization, as opposed to depolarization, is not a triggered phenomenon following an orderly sequence, hence the dissimilarity between their inscribed electrocardiographic waves; rather, ventricular myocytes repolarize at a time and rate determined by their intrinsic electrophysiological properties (relative concentration of ion channel types and isoforms), as well as by the preceding electrical and mechanical events that affect the former.