Ventricular Flutter

Bridging the Knowledge Gaps in Arrhythmogenic Cardiovascular Conditions: The Critical Role of Registries

One of the fundamental principles of evidence-based medicine is that clinical care should be based on data derived from appropriately designed trials, registries, and observational data from patients. The best available evidence is then used to develop guidelines for clinical care, assess quality, measure performance, and improve patient outcomes. The highest level of evidence in clinical medicine, also known as Level of Evidence A, is derived from multiple prospective randomized clinical trials (RCTs) or from meta-analysis.

Long-term Outcomes of Ventricular Tachycardia Ablation in Different Types of Structural Heart Disease

Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with structural heart disease (SHD). While implantable cardioverter-defibrillators (ICDs) have been shown to be effective in preventing sudden death due to ventricular arrhythmias, they are not able to prevent recurrent VT episodes. Antiarrhythmic drugs (AADs) have some demonstrated efficacy in preventing VT episodes, although options remain limited in patients with SHD and the degree of benefit is suboptimal.

Cardiac Arrhythmias in the Pregnant Woman and the Foetus

Neither supraventricular nor ventricular tachyarrhythmias are uncommon during pregnancy.1,2 When they are diagnosed, patients, relatives and physicians are frequently worried about ectopic beats and sustained arrhythmias.3,4 One should question whether arrhythmias should be treated in the same way as they would be outside pregnancy because all commonly used antiarrhythmic drugs cross the placenta.5 The pharmacokinetics of drugs are altered in pregnancy and blood levels need to be checked to ensure maximum efficacy and avoid toxicity.

Clinical and Diagnostic Aspects of Takotsubo Cardiomyopathy

Sato et al. first described Takotsubo-like left ventricular (LV) dysfunction in 1990.1 The name of this syndrome comes from the Japanese for octopus fishing pot, and it has become familiar among Japanese physicians. It is also known as transient LV apical ballooning syndrome, broken heart syndrome or ampulla-shaped cardiomyopathy, but nowadays most cardiologists refer to this phenomenon as takotsubo cardiomyopathy.