Left main stenting

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AXXESS™ Stent: Delivery Indications and Outcomes

A bifurcation lesion within the coronary arterial circulation is defined as a stenosis occurring at, or adjacent to, a significant division of a major epicardial coronary artery.1 Bifurcation lesions account for 1–20 % of all percutaneous coronary interventions (PCIs), and treatment remain technically challenging despite advances in PCI techniques and third-generation drug-eluting stent (DES) technology.

Cre8™ Unique Technology in Challenging Daily Practice

The use of coronary artery stents was first described in 1986, and percutaneous coronary intervention (PCI) involving stenting is now routine practice. However the problem of restenosis, caused by neointimal tissue growth, led to the development of drug-eluting stents (DES), which allow controlled release of antiproliferative drugs at the arterial wall.1 The use of DES has significantly improved clinical outcomes compared to bare metal stents (BMS).2,3 But safety issues emerged with the use of DES.

Clinical Impact of Stent Design

As the role of percutaneous coronary intervention (PCI) has evolved, inevitably, so too has the technology associated with this specialty. Initially, plain old balloon angioplasty (POBA) was developed as a strategy to ‘stretch’ focal stenoses within the coronary arteries leading to a relief from ischaemia and angina. Whilst potentially of great benefit to some patients, POBA was beset by a series of Achilles’ heels.

The Role of Self-expanding Stents in Patients with Atypical Coronary Anatomy

Significant advances have been made with new generation stents to further improve the results of percutaneous coronary intervention (PCI) and outcomes for patients. Drug-eluting stents introduced in the early 2000s, thinner strut stent platforms, and bioabsorbable polymers and stents are among these developments.1 Despite these advances, there remain some areas where optimal stenting continues to be a challenge, in some cases affecting patient outcome.

The Role of the Transradial Approach for Complex Coronary Interventions in Patients with Acute Coronary Syndrome

An invasive strategy including percutaneous coronary intervention (PCI) improves clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) and in high-risk patients with non-ST-segment elevation acute coronary syndrome (NSTEACS).1,2 The femoral approach (TFA) is the preferred and most widely used percutaneous access site in most cardiac catheterisation laboratories worldwide.