Left Ventricular Remodelling: A Problem in Search of Solutions

The term cardiac remodelling (REM) is used to define changes that produce geometrical rearrangement of the normal structures of the heart, together with complex biological and molecular alterations. REM affects the heart at the level of the cardiomyocyte, the blood vessels and the extracellular matrix. Proliferation of the latter, resulting in fibrosis, is one of the hallmarks of pathological REM.1,2 REM represents a major cause of heart failure as well as cardiac morbidity and mortality.

What is Takotsubo (Stress) Cardiomyopathy?

Takotsubo cardiomyopathy (TC) or syndrome was first described more than 2 decades ago by Dote and colleagues in Japan, but has since been increasingly recognised around the world.1 Takotsubo is the Japanese name for a the traditional octopus trapping pot that has a round bottom and narrow neck, resembling the appearance the left ventricle during the acute presentation (see Figure 1).2 Although, as early as the 1980s, sporadic cases from Europe had des

Study links obesity and mood disorders with increased peripartum cardiomyopathy risk

By David Ramsey, Heart Failure 2015, Seville, Spain

Anxiety, depression, bipolar disorder and obesity all place pregnant women at risk of peripartum cardiomyopathy (PPCM), according to a study including nearly 7.5 million pregnant women, presented at Heart Failur 2015. The mood disorders doubled the risk whilst obesity led to a 1.7-fold increase.

14th Genoa Meeting On Hypertension, Diabetes And Renal Diseases 2015

The 14th Genoa Meeting on “Hypertension, Diabetes and Renal Diseases” will be held in Genoa, Italy, from 26 to 28 February 2015.

The city of Genoa is a beautiful sea-resort area, facing the Ligurian Sea; the climate is very nice and the surroundings are really impressive. The city is a unique and beautiful land, with very important historical backgrounds.

The Nicholas Fortuin Cardiovascular Topics At Johns Hopkins 2015

This symposium is clinically oriented, including case presentations, updates on clinical practice and reviews of multi-center trials data, and it emphasizes the scientific underpinnings of a cardiology practice. Subjects range from basic mechanisms underlying heart rate regulation to clinical lipid management, given by a faculty who are in day-to-day practice, drawn from the Hopkins Cardiology Division and related specialties of cardiac and vascular surgery, neurology and endocrinology.

The Million Hearts Initiative - Targeting Key Drivers of Cardiovascular Mortality from a Medical Specialty Society Perspective

The past decade has seen impressive advances in cardiovascular (CV) care and reductions in patient mortality from CV disease (CVD). Between 1997 and 2007 (the year for which most recent final data are available), the death rate from CVD declined by 27.8 %. The actual number of CVD deaths per year declined by 14.2 % over this period. Meanwhile, the death rate for stroke fell by 44.8 % in the same decade-long period.1

Excess Body Weight and Coronary Artery Disease - Associated Risks, the Obesity Paradox, and Implications for Cardiac Rehabilitation

Excess body weight in the form of adipose tissue is receiving a great deal of attention, given its profound detrimental implications for health and the burden it places upon the healthcare system. Body mass index (BMI) is perhaps the most commonly used measure for classifying subjects as either normal weight (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), or obese (≥30 kg/m2). While the BMI approach clearly has limitations, its general relationship to adiposity and ability to provide health/prognostic information warrants attention.